辛鵬洋，博士，教授,，博士生導(dǎo)師
河南省優(yōu)秀青年科學(xué)基金獲得者（2021年入選）
E-Mail：[email protected]
教育經(jīng)歷：
2012.9——2015.6 復(fù)旦大學(xué) 獲博士學(xué)位
2009.9——2012.6?? 河南師范大學(xué)?? 獲碩士學(xué)位
2005.9——2009.6 許昌學(xué)院 獲學(xué)士學(xué)位
工作經(jīng)歷：
2023.4——至今 河南師范大學(xué) 抗病毒性傳染病創(chuàng)新藥物全國重點實驗室
2022.10——2023.4 河南師范大學(xué) 省部共建國家重點實驗室（籌）
2015.7——2022.10 河南師范大學(xué) 化學(xué)化工學(xué)院
研究領(lǐng)域與興趣：
超分子化學(xué)、化學(xué)生物學(xué),。構(gòu)建有機(jī)超分子體系模擬生物大分子的結(jié)構(gòu)與功能,，并進(jìn)一步研究其在生物醫(yī)藥方面的潛在應(yīng)用，在Acc. Chem. Res., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Sci.以及Green Chem.等國內(nèi)外具有重要影響力的期刊上發(fā)表論文多篇,。
近年來主持的主要科研項目：
1,、國家自然科學(xué)基金-面上項目，2022,，在研,，主持
2、國家自然科學(xué)基金-聯(lián)合基金,，2020,，結(jié)項，主持
3,、河南省優(yōu)秀青年科學(xué)基金,，2021，結(jié)項,，主持
4,、河南省高等學(xué)校重點科研項目-基礎(chǔ)研究專項，2021,，在研,，主持
5、河南師范大學(xué)國家自然科學(xué)基金面上項目培育項目,，結(jié)項,，主持
6、國家自然科學(xué)基金青年基金,，結(jié)項,，主持
7,、河南省2016年科技發(fā)展計劃-基礎(chǔ)與前沿技術(shù)研究，結(jié)項,，主持
代表性論文：
1.Linlin Mao?, Shuaimin Hou?, Linlin Shi, Jingjing Guo*, Bo Zhu, Yonghui Sun*, Junbiao Chang and Pengyang Xin*, Synthetic anion channels: achieving precise mimicry of the ion permeation pathway of CFTR in an artificial system, Chem. Sci., 2025, 16, 371-377. (通訊作者)
2.Linlin Shi, Wen Zhao, Zhihui Jiu, Jingjing Guo*, Qiuhui Zhu, Yonghui Sun, Bo Zhu,Junbiao Chang and Pengyang Xin*, Redox-Regulated Synthetic Channels: Enabling Reversible Ion Transport by Modulating the Ion-Permeation Pathway, Angew. Chem. Int. Ed. 2024, 63, e202403667.(通訊作者)
3.Bowen Ren, Yonghui Sun*, Pengyang Xin*, Recent advance in Artificial Anion Channels and Their Selectivity, ChemPlusChem, 2024, e202400466.(通訊作者)
4.Pengyang Xin*, Wenke Ren, Qiuhui Zhu, Jie Wang, Yonghui Sun*, Junbiao Chang and Gongming Zhu*, Synthetic cation channel: reconstructing the ion permeation pathway of TRPA1 in an artificial system, RSC Adv., 2024, 14, 26933-26937. (通訊作者)
5.Shouwei Zhang, Jinfeng Wang, Andriy Yaroshchuk, Qiujiao Du, Pengyang Xin, Merlin L. Bruening*, and Fan Xia*, Addressing Challenges in Ion-Selectivity Characterization in Nanopores, J. Am. Chem. Soc.2024, 146, 11036-11042.
6.Pengyang Xin,* Linqi Xu, Wenpei Dong, Linlin Mao, Jingjing Guo,* Jingjing Bi, Shouwei Zhang, Yan Pei, Chang-Po Chen*, Synthetic K+ Channels Constructed by Rebuilding the Core Modules of Natural K+ Channels in an Artificial System. Angew. Chem. Int. Ed., 2023, e202217859. (Hot Paper, 通訊作者,，IF = 16.823)
7.Qishuo Zhong, Yin Cao, Xiaopan Xie, Yuhang Wu, Zhiqing Chen, Qiuping Zhang, Chunyan Jia, Zhen Wu, Pengyang Xin, Xiaosheng Yan, Zhiping Zeng, Changliang Ren*,Non-Covalently Stapled H+/Cl? Ion Channels Activatable by Visible Light for Targeted Anticancer Therapy, Angew. Chem. Int. Ed., 2023, 63, e202314666.
8.Jingjing Guo*, Yiqiong Bao, Mengrong Li, Shu Li, Lili Xi, Pengyang Xin, Lei Wu, Huanxiang Liu, Yuguang Mu, Application of computational approaches in biomembranes: From structure to function, WIREs Comput. Mol. Sci., 2023, 13, e1679.
9.Pengyang Xin,* Lingyu Zhao, Linlin Mao, Linqi Xu, Shuaimin Hou, Huiyuan Kong, Haodong Fang, Haofeng Zhu, Tao Jiang, Chang-Po Chen*, Effect of Charge Status on the Ion Transport and Antimicrobial Activity of Synthetic Channels. Synthetic Channels. Chem. Commun.,2020,56, 13796-13799.(通訊作者，IF = 5.996)
10.Pengyang Xin,* Huiyuan Kong, Yonghui Sun, Lingyu Zhao, Haodong Fang, Haofeng Zhu, Tao Jiang, Jingjing Guo, Qian Zhang, Wenpei Dong, Chang-Po Chen*,Artificial K+ Channels Formed by Pillararene-Cyclodextrin Hybrid Molecules: Tuning Cation Selectivity and Generating Membrane Potential, Angew. Chem. Int. Ed.,2019,58, 2779-2784. (通訊作者,，IF = 12.102)
11.Pengyang Xin,* Si Tan, Yaodong Wang, Yonghui Sun, Yan Wang, Yuqing Xu and Chang-Po Chen*,Functionalized hydrazide macrocycle ion channels showing pH-sensitive ion selectivities, Chem. Commun.,2017,53, 625-628. (通訊作者,，IF = 6.319)
12.Pengyang Xin,* Si Tan, Yonghui Sun, Qiaojv Ren, Wenpei Dong, Jingjing Guo, Tao Jiang and Chang-Po Chen,* One-pot formation of hydrazide macrocycles with modified cavities: an example of pH-sensitive unimolecular cation channels, Chem. Commun.,2017,53, 5322-5325.(通訊作者，IF = 6.319)
13.Pengyang Xin,* Yonghui Sun, Huiyuan Kong, Yaodong Wang, Si Tan, Jingjing Guo, Tao Jiang, Wenpei Dong* and Chang-Po Chen*,A unimolecular channel formed by dual helical peptide modified pillar[5]arene: correlating transmembrane transport properties with antimicrobial activity and haemolytic toxicity, Chem.Commun.,2017,53, 11492-11495. (通訊作者,，IF = 6.319)
14.Min Zhang, Ping-Ping Zhu ,Pengyang Xin, Wen Si, Zhan-Ting Li, and Jun-Li Hou*,Synthetic Channel Specifically Inserts into the Lipid Bilayer of GramPositive Bacteria but not that of Mammalian Erythrocytes, Angew. Chem. Int. Ed.,2017,56, 2999-3003. (IF = 11.994)
15.Lingjun Li* , Qianqian Li, Shengqiang Ding,Pengyang Xin, Yuqin Zhang, Shenlong Huang and Guisheng Zhang*, ADP-ribosyl-N3: A Versatile Precursor for Divergent Syntheses of ADP-ribosylated Compounds, Molecules,2017,22, 1346. (IF = 2.861)
16.Pengyang Xin, Pingping, Zhu, Pei Su, Jun-Li Hou* and Zhan-Ting Li*, Hydrogen-Bonded Helical Hydrazide Oligomer and Polymer That Mimic the Ion Transport of Gramicidin A, J. Am. Chem. Soc.,2014,136, 13078-13081.(第一作者, IF = 12.113)
17.Pengyang Xin, Liang Zhang, Pei Su, Jun-Li Hou* and Zhan-Ting Li*, Hydrazide macrocycles as effective transmembrane channels for ammonium. Chem. Commun.,2015, 47,11140-11142. (第一作者,，IF = 6.834)
18.Peng-Yang Xin, Hong-Ying Niu, Gui-Rong Qu* Rui-Fang Ding, Hai-Ming Guo*, Nickel catalyzed alkylation of N-aromatic heterocycles with Grignard reagents through direct C–H bond functionalization. Chem. Commun.,2012,48, 6717- 6719. (第一作者，IF = 6.834)
19.Gui-Rong Qu,*Peng-Yang Xin,Hong-Ying Niu, Dong-Chao Wang, Rui-Fang Ding, Hai-Ming Guo*, Nickel-catalyzed sp2C–H bonds arylation of N-aromatic heterocycles with Grignard reagents at room temperature. Chem. Commun.,2011,47,11140-11142. (除導(dǎo)師外第一作者,，IF = 6.834)
20.Hai-Ming Guo,*Peng-Yang Xin, Hong-Ying Niu, Gui-Rong Qu*, Microwave irradiated C6-functionalization of 6-chloropurine nucleosides with various mild nucleophiles under solvent-free conditions. Green Chem.,2010,12, 2131-2134. (除導(dǎo)師外第一作者，IF = 8.02)
21.Gui-Rong Qu,*Peng-Yang Xin, Hong-Ying Niu,Hai-Ming Guo,* Microwave promoted palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of 6-chloropurines with sodium tetraarylborate in water. Tetrahedron,2011,67,9099- 9103. (除導(dǎo)師外第一作者,，IF = 2.803)
22.Yingtang Zhang,* Pengyang Xin,*Qiufeng Yao, Electrochemical performance of LiFePO4/C synthesized by sol-gel method as cathode for aqueous lithium ion batteries. J. Alloy. Compd.,2018,74,404-408. (通訊作者,，IF = 3.779)
23.Wen Si, Pengyang Xin, Zhan-Ting Li, Jun-Li Hou,* Tubular Unimolecular Artificial Transmembrane Channels: Construction Strategies and Transport Activities. Acc. Chem. Res.,2015,48,1612-1619. (IF = 22.323)
24.Qian Zhang,*Chun-Hang Zhang, Jun-Hui Yang, Peng-Yang Xin, Xiao-Peng Xuan, Jian-Ge Wang, Na-Na Ma, Hai-Ming Guo and Gui-Rong Qu, A four-unit [c2]daisy chain connected by hydrogen bonds. Chem. Commun.,2015,51, 15253-15256.(IF = 6.834)
25.Yu-Qin Jiang, Kai Wu, Qian Zhang, * Ke-Qing Li, Yan-Yan Li, Peng-Yang Xin, Wei-Wei Zhang and Hai-Ming Guo*, A dual-responsive hyperbranched supramolecular polymer constructed by cooperative host–guest recognition and hydrogen-bond interactions. Chem. Commun.,2018,54, 13821-13824.(IF = 6.834)
26.辛鵬洋，牛紅英,，渠桂榮,，楊西寧，郭海明,*四芳基硼鈉的簡便合成.合成化學(xué),，2011,19,671-672.
27.祝平平,，辛鵬洋，侯軍利*,，黎占亭*,乙酰膽堿經(jīng)人工通道的跨膜輸送.Chin. J. Org. Chem.,2015,35, 1994-1998.
28.祝平平,，辛鵬洋，侯軍利*,，黎占亭*,間苯二甲酸自組裝形成的人工跨膜離子通道.中國科學(xué):化學(xué),2015,45,624-628.
29.郭海明*,李璞,辛鵬洋,王東超,牛紅英,渠桂榮*,微波促進(jìn)的6-位磷功能化的非環(huán)嘌呤核苷類似物的合成.中國科學(xué):化學(xué),2010,40, 963-966.