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李用芳

發(fā)布時(shí)間:2017-12-29






姓名:李用芳

職稱:副教授/碩導(dǎo)師

辦公電話:0373-3326340

電子郵箱:[email protected]








個(gè)人簡介:

    河南師大生科院學(xué)士,、碩士,以色列本古里安大學(xué)博士,,美國俄克拉荷馬州立大學(xué)博士后及研究助理教授(2008-2015),。在Trends Plant Sci., Plant J., Nucleic Acids Res., New Phytol., RNA等期刊上發(fā)表Sci期刊論文20余篇,,其中高被引論文2篇,,單篇論文引用次數(shù)達(dá)339次,216次,。同時(shí)為Springer出版的五部學(xué)術(shù)專著撰寫5章專題?,F(xiàn)主持國家自然科學(xué)基金面上基金一項(xiàng)

研究領(lǐng)域:

小RNA與植物的生長發(fā)育和脅迫應(yīng)答 

轉(zhuǎn)錄后調(diào)控機(jī)理

主要學(xué)術(shù)及社會(huì)兼職:
中國生物化學(xué)與分子生物學(xué)學(xué)會(huì)河南省分會(huì)副理事長
主持或參加科研項(xiàng)目情況:

1.MicroRNA介導(dǎo)的轉(zhuǎn)錄后調(diào)控在冬小麥春化過程中的作用機(jī)理研究,國家自然科學(xué)基金面上基金,。主持, 2018-2021,。 

2.GhACR1調(diào)控棉花耐鹽的機(jī)理研究,國家自然科學(xué)基金,,參與,,2017-2019. 

3.Building Oklahoma's leadership in cellulosicbioenergy. 美國國家自然科學(xué)基金NSF-EPSCoR. 參與,2008-2013。 

4.Improving abiotic stress tolerance byengineering microRNA398 resistant superoxide dismutases in Rice and Tomato. 美國農(nóng)業(yè)部USDA-NRI, 參與,,2008-2011,。 

5.Nanocarrier-mediated Targeting ofBioscavengers to the Red Blood Cell for Prolonged circlulation,美國國防部 DTRA項(xiàng)目, 參與,2013-2017,。 

6.Role of Arabidopsis RNA binding proteins instress signaling,。Oklahoma Center forAdvancement of Science and Technology,參與,,2012-2014.

學(xué)術(shù)成果:

代表性論文:

1. LiYF, Zheng Y, Addo-Quaye C, Zhang L, Saini A, Jagadeeswaran G, Axtell MJ,Zhang W and Sunkar R (2010) Transcriptome-wide identification of microRNAtargets in rice. Plant J. 62(5): 742-759 (SCI TOP期刊,,高被引論文,引用261次) 

2. Sunkar R, Li YF, Jagadeeswaran G (2012). Functions of microRNAs in plantstress responses. Trends Plant Sci. 17(4):196-203 (SCI TOP期刊,高被引論文, 引用480次)

3. Zheng Y, Li YF*, Sunkar R & Zhang W (2013). SeqTar: An Effective Methodfor Identifying MicroRNA Guided Cleavage Sites from Degradome of PolyadenylatedTranscripts in Plants. Nucleic Acids Research. 40(4):e28 (SCI TOP期刊.*: 共同第一) 

4. Li, YF., Zhao, M., Wang, M., Guo, J., Wang, L., Ji, J., Qiu,Z., Zheng, Y., and Sunkar, R. (2019). An improved method of constructingdegradome library suitable for sequencing using Illumina platform. PlantMethods 15.

5. Li, YF., Wei, K., Wang, M., Wang, L., Cui, J., Zhang, D., Guo,J., Zhao, M., and Zheng, Y. (2019). Identification and Temporal ExpressionAnalysis of Conserved and Novel MicroRNAs in the Leaves of Winter Wheat Grownin the Field. Front Genet 10, 779.

6. Li, YF., Zheng, Y.,Vemireddy, L.R., Panda, S.K., Jose, S., Ranjan, A., Panda, P., Govindan, G.,Cui, J., Wei, K., Yaish, M.W., Naidoo, G.C., and Sunkar, R. (2018). Comparativetranscriptome and translatome analysis in contrasting rice genotypes revealsdifferential mRNA translation in salt-tolerant Pokkali under salt stress. BMCGenomics 19, 935.

7. Wang, L., Wang, L., Chang, W., Li,Y., and Wang, L. (2019). MicroRNA-373 promotes the development ofesophageal squamous cell carcinoma by targeting LATS2 and OXR1. Int J BiolMarkers 34, 148-155 (通訊作者).

8. Chen, K., Liu, L., Zhang, X., Yuan, Y., Ren, S., Guo, J., Wang, Q.,Liao, P., Li, S., Cui, X., Li, Y.F.,and Zheng, Y. (2018). Phased secondary small interfering RNAs inPanaxnotoginseng. BMC Genomics 19, 41. (通訊作者)

9. LiYF, Wang Y, Kakani G& Mahalingam R (2013). Transcriptome Analysis ofHeat Stress Response In Switchgrass (Panicum Virgatum L.) BMC Plant Biol. 2013Oct 6; 13(1):153. doi: 10.1186/1471-2229-13-153.

10. LiYF, Zheng Y, Jagadeeswaran G & Sunkar R (2013). Characterization ofsmall RNAs and their target genes in wheat seedlings using sequencing-basedapproaches. Plant Science. 203-204: 17-24. 

11. Jagadeeswaran G, Li YF, Sunkar R (2014). Redox signaling mediates the expression ofa sulfate-deprivation-inducible microRNA395 in Arabidopsis. Plant J. 2014Jan;77(1):85-96. doi: 10.1111/tpj.12364 (SCI TOP期刊)

12. Jagadeeswaran G, Li YF, Sunkar R (2014). Redox signaling mediates the expression ofa sulfate-deprivation-inducible microRNA395 in Arabidopsis. Plant J. 2014Jan;77(1):85-96. doi: 10.1111/tpj.12364 (SCI TOP期刊) 

13. Zheng, Y., Chen, K., Xu, Z., Liao, P., Zhang, X., Liu, L., Wei, K.,Liu, D., Li, Y.F., Sunkar, R., andCui, X. (2017). Small RNA profiles from Panax notoginseng roots differing insizes reveal correlation between miR156 abundances and root biomass levels. SciRep 7, 9418.

14.Jagadeeswaran, G., Zheng, Y., Li, Y.F., Shukla, L.I., Matts, J., Hoyt, P., Macmil, S.L., Wiley,G.B., Roe, B.A., Zhang, W., and Sunkar, R. (2009). Cloning and characterizationof small RNAs from Medicago truncatula reveals four novel legume-specificmicroRNA families. New Phytol 184, 85-98.

15. Addo-Quaye, C., Snyder, J.A.,Park, Y.B., Li, Y.F., Sunkar, R.,and Axtell, M.J. (2009). Sliced microRNA targets and precise loop-firstprocessing of MIR319 hairpins revealed by analysis of the Physcomitrella patensdegradome. RNA 15, 2112-2121.

16. Li, X., Ding, X., Li, Y., Wang, L., and Fan, J. (2016).A TiS2 nanosheet enhanced fluorescence polarization biosensor for ultra-sensitivedetection of biomolecules. Nanoscale 8, 9852-9860.

 

專著章節(jié)

  1. Li YF, Mahalingam R, Sunkar R(2017). Isolation of Polysomal RNA for AnalyzingStress-Responsive Genes Regulated at the Translational Level in Plants. MethodsMol Biol. Humana press.1631:151-161. doi: 10.1007/978-1-4939-7136-7_9.

  2. Li Y, Muthuramalingam M,,Mahalingam M (2016),,Plant responses totropospheric ozone.,,Genetic manipulation in plants for mitigation of climatechange, Pawan Kumar Jaiwal, Rana Pratap Singh, Om Parkash, Springer press, pp1-14. 

  3. Li, YF. & Sunkar, R(2013). Global identification of small RNA targets by sequencing sliced ends ofmessenger RNAs. In Yang Y ed. Rice protocols: Methods in Molecular Biology,Humana press. 956:119-29. doi: 10.1007/978-1-62703-194-3_10

  4. Muthuramalingam M, Li YF & Mahalingam R (2014),Genomics Based Analyses of Environmental Stresses In Crop. In Gaur R.K &Sharma P Eds. Approaches to Plant Stress and Their Management .383-394. DOI10.1007/978-81-322-1620-9_22, Springer India. 

  5. Sinai A, Li YF& Sunkar R (2012). Role of microRNAs in plant adaptation to environmentstress. In Sunkar R ed. MicroRNAs in Plant Development and Stress Responses(Signaling and Communication in Plants). Springer press. pp 219-232