2007.09-2011.07,,河南農業(yè)大學,,環(huán)境工程,,工學學士
2011.09-2014.07,南開大學,,環(huán)境科學,,理學碩士
2014.09-2018.07,南開大學,,環(huán)境科學,,理學博士
2018.0–至今,河南師范大學,,環(huán)境學院,,講師(校聘副教授)
張杏麗(1987—),女,,博士,,碩士生導師。主持國家自然科學基金青年基金1項,,國家博士后面上項目1項,,參與國家自然基金面上項目3項。在Environmental Science Technology,Environment International,,Journal of Hazardous Materials, Science of the Total Environment,,Environmental Pollution,《環(huán)境科學》等國內外期刊上發(fā)表學術論文20余篇,,其中第一作者/通訊作者發(fā)表SCI論文6篇,,中文核心3篇。主要從事環(huán)境新型有機污染物及微納米污染物的生態(tài)毒理及人體健康風險評估研究,。
(1)新型環(huán)境污染物(有機污染物,,微納米污染物)在水環(huán)境中的轉化,生物富集及毒理效應,;
(2)多組學聯合(轉錄組學,、蛋白組學及代謝組學)技術揭示水生生物對污染物的分子響應機制;
主近期主要開展微塑料的環(huán)境老化過程機制及人體健康風險評估,,以及環(huán)境特征微塑料對水體中典型有機污染物生物富集及生態(tài)毒性的影響研究,。
生態(tài)毒理學會會員
擔任J. Hazard. Mater.、Sci. Total Environ.等多個期刊的審稿人
近年來主持或參與的主要科研項目:
1. 國家自然科學基金青年科學基金項目(41907349),,微塑料對有機磷阻燃劑生物跨代效應的影響及其分子機制研究,,2020.01-2022.12,主持,;
2. 中國博士后科學基金面上資助(2019M662499),,胞外聚合物調控微塑料水環(huán)境行為及生物效應的機制研究,2019.12-2022.12,主持,;
3. 國家自然科學基金面上項目(21876092),,納米結構對模擬氧化石墨烯產品環(huán)境釋放與生物效應的調控作用及分子機制研究,2019.01-2022.12,,參與,;
4. 國家自然科學基金面上項目(21677080),石墨烯納米材料對典型水生物的代謝毒性及其機理,,2017.01-2020.12,,參與;
5. 國家自然科學基金青年科學基金項目(21307061),,石墨烯在水體中的化學行為轉變及其微觀機理研究,,2014.01-2016.12,參與
代表性論文:
1. Zou, W.; Xia, M.L.; Jiang, K.; Cao, Z.G.; Zhang X.L.,* et al. Photo?oxidative degradation mitigated the developmental toxicity of polyamide microplastics to zebrafish larvae by modulating macrophage?triggered proinflammatory responses and apoptosis. Environmental Science & Technology 2020, 13888-13898.
2. Zhang, X.L. et al.Photoaging enhanced the adverse effects of polyamide microplastics on the growth, intestinal health, and lipid absorption in developing zebrafish.Environment International 2022,158, 106922.
3. Zhang, X.L.* et al.Photolytic degradation elevated the toxicity of polylactic acid microplastics to developing zebrafish by triggering mitochondrial dysfunction and apoptosis. Journal of Hazardous Materials 2021, 413,125321.
4. Zhang, X.L. et al. Integrating omics and traditional analyses to profile the synergistic toxicity of graphene oxide and triphenyl phosphate. Environmental Pollution 2020, 263,114473.
5. Zhang, X.L. et al. Molecular mechanisms of developmental toxicity induced by graphene oxide at predicted environmental concentrations. Environmental Science & Technology 2017, 51, 7861-7871.
6. Zhang, X.L. et al. Rice ingestion is a major pathway for human exposure to organophosphate flame retardants (OPFRs) in China. Journal of Hazardous Materials2016, 318, 686-693.
7. Zou, W.; Li, X.; Li, C.; Sun, Y.; Zhang, X.L., et al. Influence of Size and Phase on the Biodegradation, Excretion, and Phytotoxicity Persistence of Single-Layer Molybdenum Disulfide. Environmental Science & Technology 2020, 54, 19, 12295-12306.
8. Zou, W.; Zhou, Q.; Zhang, X.L., et al. Dissolved oxygen and visible light irradiation drive the structural alterations and phytotoxicity mitigation of single-layer molybdenum disulfide. Environmental Science & Technology 2019, 53, 7759?7769
9. Zou, W.; Zhou, Q.; Zhang, X.L., et al. Environmental transformations and phytotoxicity of single layer molybdenum disulfide regulated by human acid. Environmental Science & Technology 2018, 52, 2638?2648.
10. Zou, W.; Zhang, X.L., et al. Graphene oxide nanosheets mitigate the developmental toxicity of TDCIPP in zebrafish via activating the mitochondrial respiratory chain and energy metabolism. Science of the Total Environment 2020, 727, 138486.
11. Zou, W.; Zhou, Q.; Zhang, X.L., et al. Characterization of the effects of trace concentrations of graphene oxide on zebrafish larvae through proteomic and standard methods. Ecotoxicology and Environmental Safety 2018,159, 221–231.
12. Zou, W.; Zhang, X.L., et al. Cellular proliferation and differentiation induced by single-layer molybdenum disulfide and mediation mechanisms of proteins via the Akt-mTOR-p70S6K signaling pathway. Nanotoxicology 2017, 11, 781-793.
13. 張杏麗, 鄒威,,周啟星*.基于代謝組學技術分析磷酸三苯酯誘導斑馬魚胚胎發(fā)育毒性的分子機制.生態(tài)毒理學報 2019, 3, 79-89.
14. 張杏麗, 鄒威,,周啟星*. 鎘-八氯代二苯并呋喃復合污染土壤中紫茉莉對鎘的修復能力. 環(huán)境科學2015, 8, 3045-3055.
15. 張杏麗, 周啟星*. 土壤環(huán)境多氯二苯并二噁英/呋喃(PCDD/Fs)污染及其修復研究. 生態(tài)學雜志2013, 32,1054-1064.