楊國(guó)坤 博士/副教授
主要從事水產(chǎn)動(dòng)物內(nèi)分泌及代謝和水產(chǎn)動(dòng)物腸道益生菌研究,，對(duì)功能基因進(jìn)行發(fā)掘,，研究其對(duì)魚類生長(zhǎng)、糖脂代謝,、免疫的調(diào)控機(jī)制,。近五年來(lái)主持國(guó)家自然科學(xué)基金、河南省自然科學(xué)基金,、河南省科技攻關(guān)項(xiàng)目等5項(xiàng)，在《Frontiers in Immunology》,、《Aquaculture》等SCI期刊及國(guó)內(nèi)重要期刊發(fā)表及參與發(fā)表學(xué)術(shù)論文50余篇,，授權(quán)發(fā)明專利4項(xiàng)。
▊通訊地址
E-mail: [email protected]
電話：15090322075
地址：河南省新鄉(xiāng)市牧野區(qū)建設(shè)東路46號(hào)
▊教育背景
博士(2012/09-2017/12): 中山大學(xué),，生命科學(xué)學(xué)院,，水生生物學(xué)專業(yè)
學(xué)士(2008/09-2012/06): 佳木斯大學(xué)，生命科學(xué)學(xué)院,，生物技術(shù)專業(yè)
▊工作經(jīng)歷
2024/03- 至今：河南師范大學(xué)水產(chǎn)學(xué)院,，副教授
2018/03-2024/03：河南師范大學(xué)水產(chǎn)學(xué)院，講師
▊承擔(dān)課程
1.生物化學(xué),、水產(chǎn)動(dòng)物營(yíng)養(yǎng)與飼料實(shí)驗(yàn)(本科)
▊研究方向
1.水產(chǎn)動(dòng)物內(nèi)分泌及代謝
2. 水產(chǎn)益生菌發(fā)掘及應(yīng)用
▊科教項(xiàng)目
1) Amuc_1100介導(dǎo)TLR2/c-Jun/GIP通路調(diào)控大口黑鱸糖代謝機(jī)制研究,，國(guó)家自然科學(xué)基金青年項(xiàng)目 (32303020)，主持
2) GIP/GIPR調(diào)控草魚脂肪代謝的研究,，河南省科技攻關(guān)項(xiàng)目 (202102110259),，主持
3) GIP/GIPR對(duì)草魚脂肪沉積的調(diào)控機(jī)制研究，河南省自然科學(xué)基金 (212300410174),，主持
4) Irisin對(duì)鯉肝臟糖脂代謝的調(diào)控機(jī)制研究,，河南省高等學(xué)校重點(diǎn)科研項(xiàng)目 (20A240005),，主持
5) 胰島素對(duì)草魚肝臟糖穩(wěn)態(tài)的調(diào)控研究，河南省科技攻關(guān)項(xiàng)目 (192102110193),，主持
▊研究成果
1) Guokun Yang, Chengquan Li, Sunan Wang, Xiaomin Liang, Boya Yang,Yanmin Zhang, Xindang Zhang, Xulu Chang, Xiaolin Meng*. Molecular characterization of the grass carp bscl2 gene and its expression response to lipid accumulation, nutritional status, insulin and glucagon, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2024, 270, 110931.
2) Guokun Yang, Boya Yang, Sunan Wang, Xiaomin Liang, Chengquan Li, Yanmin Zhang, Xindang Zhang, Xulu Chang, Xiaolin Meng*. Cloning grass carp (Ctenopharyngodon idella) ccdc3 and its expression affected by nutrition state, insulin, and glucagon, Journal of Fish Biology, 2023, 15614.
3) Guokun Yang, Aixia Jiang, Huimin Cai, Fu You, Shengkui Wu, Yanmin Zhang, Xindang Zhang, Yawei Shen, Xulu Chang, Wenpan Hu, Keke Li, Xiaolin Meng*. Supplementation with Akkermansia muciniphila improved glucose metabolism disorder in common carp (Cyprinus carpio L.), Aquaculture, 2023, 2023: 739465.
4) Guokun Yang, Xiaomin Liang, Shuangyang Xu, Huimin Cai, Limei Ma, Xulu Chang, Yanmin Zhang, Liping Yang, Xiaolin Meng*. Molecular identification of Igf3 and its roles in grass carp (Ctenopharyngodon idella). Aquaculture 2022, 548.
5) Guokun Yang, Xiaomin Liang, Chaobin Qin, Liping Yang, Yanmin Zhang, Ronghua Lu, Xiao Yan, Xiaolin Meng, Guoxing Nie*. Molecular cloning, tissue distribution and functional characterization of glucose-dependent insulinotropic peptide (GIP) gene in Ctenopharyngodon idella. Aquaculture 2022, 548.
6) Guokun Yang, Xiaomin Liang, Yanle Jiang, Chengquan Li, Yanmin Zhang, Xindang Zhang, Xulu Chang, Yawei Shen, Xiaolin Meng*. Molecular Characterization of Grass Carp GIPR and Effect of Nutrition States, Insulin, and Glucagon on Its Expression, Aquaculture Nutrition, 2022, 2022: 4330251.
7) Guokun Yang, Xiaomin Liang, Yanle Jiang, Chengquan Li, Jihong Hu, Yanmin Zhang, Xindang Zhang, Xulu Chang, Wenpan Hu, Keke Li, Xiaolin Meng*. Myonectin in grass carp (Ctenopharyngodon idella): Molecular cloning and effect of nutrition state, insulin and glucagon on myonectin expression, Aquaculture Reports, 2022, 26(2022): 101306.
8) Guokun Yang, Xiaomin Liang, Jihong Hu, Chengquan Li, Wenpan Hu, Keke Li, Xulu Chang, Yanmin Zhang, Xindang Zhang, Yawei Shen, Xiaolin Meng*. Feeding tea polysaccharides affects lipid metabolism, antioxidant capacity and immunity of common carp (Cyprinus carpio L.), Frontiers in Immunology, 2022, 13: 1074198.
9) Guokun Yang, Wenli Zhao, Chaobin Qin, Liping Yang, Xiaolin Meng, Ronghua Lu, Xiao Yan, Xianglin Cao, Yanmin Zhang, Guoxing Nie*. Molecular identification of grass carp igfbp2 and the effect of glucose, insulin, and glucagon on igfbp2 mRNA expression, Fish Physiology and Biochemistry 2020, 46: 1469-1482.
10) Guokun Yang, Wenli Zhao, Chaobin Qin, Liping Yang, Xiaolin Meng, Ronghua Lu, Xiao Yan, Xianglin Cao, Yanmin Zhang, Guoxing Nie*, Igfbp3 in grass carp (Ctenopharyngodon idellus): Molecular identification and mRNA expression under glucose, insulin and glucagon, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2020, 242: 110394.
11) Guokun Yang, Beichen Chen, Caiyun Sun, Xi Yuan, Yazhou Zhang, Jingkai Qin, Wensheng Li*, Molecular identification of grouper Igfbp1 and its mRNA expression in primary hepatocytes under Gh and insulin, General and Comparative Endocrinology, 2019, 281: 137-144.
12) Guokun Yang, Qinqin Song, Caiyun Sun, Jingkai Qin, Jirong Jia, Xi Yuan, Yazhou Zhang, Wensheng Li*. Ctrp9 and adiponectin receptors in Nile tilapia (Oreochromis niloticus): Molecular cloning, tissue distribution and effects on reproductive genes, General and Comparative Endocrinology, 2018, 265: 160-173.
13) Guokun Yang, Chaobin Qin, Bin Wang, Jirong Jia, Xi Yuan, Caiyun Sun, Wensheng Li*. Molecular identification and functional analysis of CTRP9 in Epinephelus coioides. Journal of Molecular Endocrinology, 2017, 58(4): 179-191.
14) 張新黨,，孟曉林，楊國(guó)坤,，張艷敏,，常緒路，一種克氏原螯蝦的池塘精養(yǎng)方法,，2023.05.05,，中國(guó)，ZL202210564890.3
15) 秦超彬,，趙文麗,，楊國(guó)坤，聶國(guó)興,，楊麗萍,，孟曉林，盧榮華,，草魚AdiponectinA基因,、編碼蛋白及其應(yīng)用，2022.11.08,，中國(guó),，ZL201910522917.0
16) 李文笙，楊國(guó)坤,，斜帶石斑魚insulin基因,、編碼蛋白及其應(yīng)用, 2021.07.27,中國(guó), ZL201711001284.6
17) 李文笙，楊國(guó)坤,，秦超彬,，斜帶石斑魚ctrp9基因、編碼蛋白及其應(yīng)用,， 2016.06.15,，中國(guó), ZL201410380895.6
▊獲獎(jiǎng)榮譽(yù)
范蠡科學(xué)技術(shù)獎(jiǎng) 二等獎(jiǎng)
