常緒路 博士,、副教授、博士生導(dǎo)師
常緒路，河南省優(yōu)秀青年科學(xué)基金獲得者,、河南省高等學(xué)校青年骨干教師培養(yǎng)計劃入選者,。從事水產(chǎn)微生物資源與應(yīng)用研究工作，主持國家自然科學(xué)基金,、河南省優(yōu)秀青年科學(xué)基金,、河南省科技攻關(guān)等項(xiàng)目10余項(xiàng)。在國內(nèi)外學(xué)術(shù)期刊《Journal of Hazardous Materials》,、《Aquaculture》,、《Fish & Shellfish Immunology》、《Probiotics and Antimicrobial Proteins》,、《Aquaculture Reports》,、《Aquaculture Nutrition》、《水產(chǎn)學(xué)報》等發(fā)表研究論文70余篇,。主講課程《微生物學(xué)》入選河南省本科一流課程,、河南省第二批課程思政樣板課程和河南省研究性教學(xué)示范課程，發(fā)表教改論文5篇,，參編教材1部,。
▊通訊地址
地址：河南省新鄉(xiāng)市建設(shè)路河南師范大學(xué)東區(qū)實(shí)訓(xùn)樓211
郵編：453007
E-mail: [email protected]
電話：0373-3326639
▊教育背景
博士(2011/09-2016/06): 武漢大學(xué)，生命科學(xué)學(xué)院,，微生物學(xué)專業(yè)
學(xué)士(2007/09-2011/06): 河南師范大學(xué),，生命科學(xué)學(xué)院，生物科學(xué)專業(yè)
▊工作經(jīng)歷
2022.02-至今,，河南師范大學(xué)水產(chǎn)學(xué)院,，副教授
2016.07-2022.01，河南師范大學(xué)水產(chǎn)學(xué)院,，講師
▊承擔(dān)課程
1.微生物學(xué),、微生物實(shí)驗(yàn),、生物統(tǒng)計與試驗(yàn)設(shè)計 (本科)
2.生物統(tǒng)計學(xué) (研究生)
▊研究方向
1. 水產(chǎn)微生物資源與應(yīng)用
2. 水生動物腸道微生物與環(huán)境互作
▊科教項(xiàng)目
1. 表面蛋白BslA介導(dǎo)的魚源貝萊斯芽孢桿菌腸道定植規(guī)律與機(jī)制研究, 國家自然科學(xué)基金-面上項(xiàng)目，2024-2027,，立項(xiàng)在研,，主持。
2. 表面蛋白BslA拮抗嗜水氣單胞菌粘附定植黃河鯉腸道的作用效果與機(jī)制,，河南省優(yōu)秀青年科學(xué)基金,，2025-2027，立項(xiàng)在研,，主持,。
3. 河南省高等學(xué)校青年骨干教師培養(yǎng)計劃，2024-2026,，立項(xiàng)在研,，主持。
4. 凝結(jié)芽孢桿菌緩解鎘暴露導(dǎo)致的鯉魚腸道屏障損傷的作用及機(jī)制,，國家自然科學(xué)基金-青年項(xiàng)目,，2020-2022，結(jié)項(xiàng),，主持,。
5. 貝萊斯芽孢桿菌抗菌肽Surfactin 在大口黑鱸疾病防控中的應(yīng)用，河南省重點(diǎn)科技攻關(guān)項(xiàng)目,，2023-2024,，立項(xiàng)在研，主持,。
6. 貝萊斯芽孢桿菌聯(lián)合葡萄糖酸鈉替代抗生素在黃河鯉健康養(yǎng)殖中的應(yīng)用,，新鄉(xiāng)市科技攻關(guān),，2022-2023,，立項(xiàng)在研，主持,。
7. 凝結(jié)芽孢桿菌緩解鎘暴露導(dǎo)致鯉魚毒性損傷的作用與機(jī)制,，河南省重點(diǎn)科技攻關(guān)項(xiàng)目，2020-2021,，結(jié)項(xiàng),，主持。
8. 高效低溫聚磷工程菌的構(gòu)建及其在富營養(yǎng)化水體除磷中的應(yīng)用,，河南省重點(diǎn)科技攻關(guān)項(xiàng)目, 2019-2020,，結(jié)項(xiàng)，主持,。
9. 一株分離自北極的耐低溫聚磷菌在水產(chǎn)養(yǎng)殖廢水除磷中的應(yīng)用,，河南省高等學(xué)校重點(diǎn)科研項(xiàng)目,，2018-2019，結(jié)項(xiàng),，主持,。
▊研究成果
1. Chang Xulu; Yun Lili; Liu Zhikun; Shen Yihao; Feng Shikun; Yang Guokun; Meng Xiaolin*. Antagonistic effects and the underlying mechanisms of Bacillus velezensis and its antibacterial peptide LCI against Aeromonas hydrophila infection in Largemouth Bass. Probiotics and Antimicrobial Proteins, 2024, 10329
2. Chang Xulu; Shen Yihao; Yang Mingqi; Yun Lili; Liu Zhikun; Feng Shikun; Yang Guokun; Meng Xiaolin*; Su Xi*. Antipsychotic drug-induced behavioral abnormalities in common carp: The potential involvement of the gut microbiota-brain axis. Journal of Hazardous Materials, 2024, 472:134444
3. Wang Yawei; Huang Zhenyi; Gui Zewei; Yang Boya; You Fu; Yang Guokun; Zhang Xindang; Chang Xulu*; Meng Xiaolin*. Supplementation with Akkermansia muciniphila improved intestinal barrier and immunity in zebrafish (Danio rerio). Fish & Shellfish Immunology, 2024, 154: 109935
4. Yun Lili； Kang Meiru; Shen Yihao; Feng Junchang; Yang Guokun; Zhang Jianxin; Meng Xiaolin*; Chang Xulu*. Dietary Bacillus velezensis R-71003 and sodium gluconate improve antioxidant capacity, immune response and resistance against Aeromonas hydrophila in common carp. Fish & Shellfish Immunology, 2023, 139:108921
5. Chang Xulu*; Kang Meiru; Yun LiLi; Shen Yihao; Feng Junchang; Yang Guokun; Zhang Jianxin; Meng Xiaolin*. Sodium gluconate increases Bacillus velezensis R-71003 growth to improve the health of the intestinal tract and growth performance in the common carp (Cyprinus carpio L.). Aquaculture, 2023, 563(01):738980
6. Chang Xulu; Shen Yihao; Yun Lili; Wang Xianfeng; Feng Junchang; Yang Guokun; Meng Xiaolin; Zhang Jianxin; Su Xi*; The antipsychotic drug olanzapine altered lipid metabolism in the common carp (Cyprinus carpio L.): Insight from the gut microbiota-SCFAs-liver axis, Science of The Total Environment, 2023, 856:159054
7. Zhang Jianxin; Huang Mengyuan; Feng Junchang; Chen Yongyan; Li Meng; Meng Xiaolin; Chang Xulu*. Effect of beneficial colonization of Bacillus coagulans NRS 609 on growth performance, intestinal health, antioxidant capacity, and immune response of common carp (Cyprinus carpio L.). Aquaculture Nutrition,2023:1451394
8. Kang Meiru; Su Xi; Yun Lili; Shen Yihao; Feng Junchang; Yang Guokun; Meng Xiaolin; Zhang Jianxin; Chang Xulu*. Evaluation of probiotic characteristics and whole genome analysis of Bacillus velezensis R-71003 isolated from the intestine of common carp (Cyprinus carpio L.) for its use as a probiotic in aquaculture. Aquaculture Reports, 2022, 25:101254
9. Chang Xulu*; Chen Yongyan; Feng Junchang; Huang Mengyuan; Zhang Jianxin; Amelioration of Cd-induced bioaccumulation, oxidative stress and immune damage by probiotic Bacillus coagulans in common carp (Cyprinus carpio L.), Aquaculture Reports, 2021, 20: 100678
10. Chang Xulu; Kang Meiru; Shen Yihao; Yun Lili; Yang Guokun; Zhu Lei; Meng Xiaolin; Zhang Jianxin; Su Xi*. Bacillus coagulans SCC-19 maintains intestinal health in cadmium-exposed common carp (Cyprinus carpio L.) by strengthening the gut barriers, relieving oxidative stress and modulating the intestinal microflora, Ecotoxicology and Environmental Safety, 2021, 228: 0-112977
11. Zhang Jianxin; Huang Mengyuan; Feng Junchang; Chen Yongyan; Li Meng; Chang Xulu*. Effects of dietary Bacillus licheniformis on growth performance, intestinal morphology, intestinal microbiome, and disease resistance in common carp (Cyprinus carpio L.) Aquaculture International, 2021, 29(3): 1343-1358
12．Chang Xulu; Wang Xianfeng; Feng Junchang; Su Xi; Liang Junping; Li Hui; Zhang Jianxin*. Impact of chronic exposure to trichlorfon on intestinal barrier, oxidative stress, inflammatory response and intestinal microbiome in common carp (Cyprinus carpio L.), Environmental Pollution, 2020, 259:113846
13．Chang Xulu; Liu Ping; Feng Junchang; Su Xi; Huang Mengyuan; Chen Yongyan; Zhang Jianxin*; Li Baohua*. Impact of chronic exposure to the ionic liquid ([C8mim][PF6]) on intestinal physical barrier, immunological barrier and gut microbiota in common carp (Cyprinus carpio L.), Environmental Research, 2020, 189:109919
14．Chang Xulu; Li Hui; Feng Junchang; Chen Yongyan; Nie Guoxing; Zhang Jianxin?. Effects of cadmium exposure on the composition and diversity of the intestinal microbial community of common carp (Cyprinus carpio L.), Ecotoxicology and Environmental Safety, 2019, 171: 92-98
15．Chang Xulu; Feng Junchang; Guo Xiangrui; Huang Mengyuan; Nie Guoxing; Zhang Jianxin*. Dietary supplementation with Rehmannia glutinosa affects the composition of intestinal microorganisms in common carp, Journal of Basic Microbiology, 2018, 58(12):1023-1032
▊獲獎榮譽(yù)
1．首屆高校大學(xué)生水產(chǎn)類創(chuàng)新實(shí)踐能力大賽全國總決賽優(yōu)秀指導(dǎo)教師
2. 2023年度河南師范大學(xué)優(yōu)秀黨務(wù)工作者
3. 2021年度河南師范大學(xué)急難險重先進(jìn)個人
4．2020年度河南師范大學(xué)優(yōu)秀共產(chǎn)黨員
5．2018年度河南師范大學(xué)文明教師
