聶國興 博士 教授
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| 第三屆華東地區(qū)水產(chǎn)動(dòng)物營養(yǎng)與飼料科技論壇（2012,，杭州） | 第一屆中部地區(qū)水產(chǎn)飼料實(shí)用技術(shù)論壇（2013,，武漢） | |
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| 第一屆中部地區(qū)水產(chǎn)飼料實(shí)用技術(shù)論壇（2013,，武漢） | 中美國際研究和教育伙伴計(jì)劃(PIRE)聯(lián)合采樣（2013,，騰沖） | |
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| 中美國際研究和教育伙伴計(jì)劃(PIRE)聯(lián)合采樣（2013,，騰沖） | 中美國際研究和教育伙伴計(jì)劃(PIRE)聯(lián)合采樣（2013,，騰沖） | |
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| 第九屆世界華人魚蝦營養(yǎng)學(xué)術(shù)研討會(huì)（2013,，廈門） | 第九屆世華會(huì)墻報(bào)總結(jié)（2013,，廈門） | |
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| 第九屆世界華人魚蝦營養(yǎng)學(xué)術(shù)研討會(huì)（2013，廈門） | 中國高校水產(chǎn)學(xué)科發(fā)展聯(lián)席會(huì)（2013,，寧波） |
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一,、個(gè)人簡介 聶國興，男,，1971年3月生,，河南長垣人，博士,，教授,，水產(chǎn)學(xué)院院長，河南省水產(chǎn)動(dòng)物養(yǎng)殖工程技術(shù)研究中心主任,。系河南省優(yōu)秀青年科技專家,、河南省高?？萍紕?chuàng)新人才、河南師范大學(xué)學(xué)術(shù)委員會(huì)委員,、河南省現(xiàn)代農(nóng)業(yè)產(chǎn)業(yè)技術(shù)體系崗位專家,、水產(chǎn)養(yǎng)殖省級(jí)重點(diǎn)學(xué)科學(xué)術(shù)帶頭人、河南省教學(xué)標(biāo)兵,、教育部農(nóng)業(yè)推廣碩士漁業(yè)領(lǐng)域培養(yǎng)協(xié)作組成員,、河南省水產(chǎn)技術(shù)推廣工作技術(shù)專家組副組長、河南省漁業(yè)經(jīng)濟(jì)研究會(huì)副理事長,、河南省漁業(yè)協(xié)會(huì)副會(huì)長,、中國水產(chǎn)學(xué)會(huì)會(huì)員、中國水產(chǎn)學(xué)會(huì)動(dòng)物營養(yǎng)與飼料專業(yè)委員會(huì)委員,、中國畜牧學(xué)會(huì)飼料安全及生物技術(shù)專業(yè)委員會(huì)委員,。 二、研究領(lǐng)域 研究領(lǐng)域是水產(chǎn)動(dòng)物營養(yǎng)與飼料科學(xué),。主要研究方向?yàn)轱曈妹钢苿┚赀x育及酶學(xué)性質(zhì)研究,、魚類營養(yǎng)素轉(zhuǎn)運(yùn)生理學(xué)及漁業(yè)資源評(píng)估與利用。 飼用酶制劑菌株選育及酶學(xué)性質(zhì)研究方面,，結(jié)合水產(chǎn)動(dòng)物營養(yǎng)特點(diǎn),，關(guān)注特殊生態(tài)環(huán)境（如：熱泉、鹽湖等）,，尤其是高溫環(huán)境中豐富的微生物資源,。從極端生境中分離細(xì)菌、放線菌和真菌,，以純培養(yǎng)技術(shù)為基礎(chǔ),，結(jié)合免培養(yǎng)技術(shù)，篩選能夠產(chǎn)生纖維素酶,、半纖維素酶（木聚糖酶,、β-葡聚糖酶、β-甘露聚糖酶和漆酶）及蛋白酶,、淀粉酶的菌株,；從上述菌株中獲取基因資源，采用基因工程技術(shù),，定向獲取具有特定功能的飼用酶制劑,；開發(fā)系列酶制劑穩(wěn)定劑、低聚木糖,、低聚甘露糖等下游產(chǎn)品,。先后主持并完成“固定化木聚糖酶的理性設(shè)計(jì)與生產(chǎn)技術(shù)研究”、 “耐高溫木聚糖酶產(chǎn)酶菌株的選育”等15項(xiàng)省廳級(jí)重大,、重點(diǎn)科研項(xiàng)目及“木聚糖酶穩(wěn)定劑的研制與產(chǎn)業(yè)化生產(chǎn)”,、“酶法制備低聚木糖技術(shù)”等10項(xiàng)企業(yè)委托項(xiàng)目,。科研成果“稻田養(yǎng)殖美國青蛙高產(chǎn)技術(shù)及原理的研究”2000年獲得河南省科技進(jìn)步三等獎(jiǎng),、“小麥抗?fàn)I養(yǎng)因子及其降解酶研究與產(chǎn)業(yè)化開發(fā)”2003年獲得河南省科技進(jìn)步二等獎(jiǎng),、 “耐高溫木聚糖酶菌株選育、穩(wěn)定性研究及木聚糖酶在魚類飼料中的應(yīng)用”2013年獲得河南省教育廳科技成果一等獎(jiǎng),，河南省科技進(jìn)步三等獎(jiǎng),。 魚類營養(yǎng)素轉(zhuǎn)運(yùn)生理學(xué)方面，主要進(jìn)行了鯉魚,、尼羅羅非魚鈉/葡萄糖共轉(zhuǎn)運(yùn)載體,、氨基酸轉(zhuǎn)運(yùn)載體、小肽轉(zhuǎn)運(yùn)載體的組織差異,、發(fā)育變化,、營養(yǎng)調(diào)控、載體蛋白結(jié)構(gòu)與功能關(guān)系研究,。承擔(dān)了國家自然科學(xué)基金課題”鯉魚腸道Sglt1表達(dá),、結(jié)構(gòu)與轉(zhuǎn)運(yùn)活性研究（31372545）”（2014-2017）,。本項(xiàng)目在前期研究工作的基礎(chǔ)上,，參考國內(nèi)外同類研究成果，以鯉魚為實(shí)驗(yàn)對(duì)象,，綜合采用營養(yǎng)學(xué),、免疫學(xué)、組織化學(xué),、細(xì)胞生物學(xué),、分子生物學(xué)等實(shí)驗(yàn)技術(shù)，從基因轉(zhuǎn)錄,、翻譯和蛋白水平研究鯉魚Sglt1 表達(dá),、結(jié)構(gòu)、轉(zhuǎn)運(yùn)活性及Sglt1-Glut2的表達(dá)關(guān)聯(lián),，旨在闡明鯉魚腸道Sglt1表達(dá)及其轉(zhuǎn)運(yùn)活性的晝夜節(jié)律,，探討日糧中Na+濃度、葡萄糖濃度對(duì)Sglt1表達(dá)及轉(zhuǎn)運(yùn)活性的調(diào)控規(guī)律,。項(xiàng)目的研究結(jié)果部分揭示了魚類糖代謝的分子機(jī)理,，可促進(jìn)糖類在水產(chǎn)動(dòng)物飼料中的科學(xué)使用。另外,，本方向承擔(dān)的項(xiàng)目還有河南省教育廳科學(xué)技術(shù)研究重點(diǎn)項(xiàng)目“鯉魚腸道肽轉(zhuǎn)運(yùn)載體PepT1表達(dá)及轉(zhuǎn)運(yùn)活性的研究（12A240001）”（2012-2014）,。 漁業(yè)資源評(píng)估方面，承擔(dān)了河南省科技攻關(guān)重點(diǎn)項(xiàng)目“河南省魚類資源調(diào)查暨優(yōu)良養(yǎng)殖品種挖掘（122102110049）”（2013-2015）和“河南水環(huán)境變化對(duì)魚類區(qū)系組成的影響（122102310357）”（2013-2015）的研究工作,。本工作的目標(biāo)是修訂1984年出版的《河南魚類志》,，建設(shè)河南省魚類標(biāo)本庫,、種質(zhì)資源庫和條形碼信息數(shù)據(jù)庫，助力河南省水產(chǎn)業(yè)的長足發(fā)展,。 三,、在研課題
四、發(fā)表論文 1,、SCI期刊論文(2011-2014) Yan-Yan Duan, Hong Ming, Lei Dong, Yi-Rui Yin, Yi Zhang, En-Min Zhou, Lan Liu, Guo-Xing Nie*, Wen-Jun Li *. Streptomyces calidiresistens sp. nov., isolated from a hot spring sediment. Antonie Van Leeuwenhoek Journal of Microbiology. 2014 (Under Review). Jun-Li Wang , Rong-Hua Lu, Chun Wu, Yan-Ting Luo, Guang Hao, Xiao Yan, Xue-Jun Li, Xiang-Hui Kong, Guo-Xing Nie*. Effects of Rehmannia glutinosa Liboseh on growth performance and immune function in common carp (Cyprinus carpio L.). Aquaculture, 2014 (Under Review). Jun-Li Wang, Xiao Yan, Guo-Xing Nie*. Peptide Transporter PepT1 in fish: physiological characteristics, protein structure , tissue distribution, expression and regulation. Molecular and Cellular Biochemistry. 2014 (Under Review). Lei Dong, Hong Ming, En-Min Zhou, Yi-Rui Yin, Lan Liu,Hui-Geng Feng, Wen-Dong Xian, Guo-Xing Nie, and Wen-Jun Li. Crenibacillus luteus gen. nov., sp. Nov., isolated from a hot spring in Tengchong, Yunnan, south-west China. International Journal of Systematic and Evolutionary Microbiology. 2014 (Revised). En-Min Zhou, Tian-Tian Yu, Lan Liu, Hong Ming, Yi-Rui Yin, Lei Dong, Min Tseng, Guo-Xing Nie, Wen-Jun Li. Geothermomicrobium tengchongense gen. nov., sp. nov., a novel member of the family Thermoactinomycetaceae. International Journal of Systematic and Evolutionary Microbiology. 2014 (Revised). Xiao-lin Meng, Xue Tian, Mei Liu, Guo-xing Nie, Keyong Jiang, Bao-jie Wang Lei Wang. Study of the transcriptomic response to copper exposure by the gill tissue of Japanese scallops (Mizuhopecten yessoensis) using deep-sequencing technology. Fish and Shellfish Immunology. 2014 (Accepted). Lei Dong, Hong Ming, Yi-Rui Yin, Yan-Yan Duan, En-Min Zhou, Guo-Xing Nie, Lan Liu, and Wen-Jun Li. Roseomonas alkaliterrae sp. nov., isolated from a alkali geothermal soil sample in Tengchong, Yunnan, south-west China. Antonie Van Leeuwenhoek Journal of Microbiology. 2014 (In Press) DOI 10.1007/s10482-014-0144-1. Liang, J. P., Li, J., Li, J. T., Liu, P., Chang, Z. Q., Nie, G. X. Accumulation and elimination of enrofloxacin and its metabolite ciprofloxacin in the ridgetail white prawn Exopalaemon carinicauda following medicated feed and bath administration. Journal of Veterinary Pharmacology and Therapeutics. 2014 (In Press) DOI: 10.1111/jvp.12115. Lei Dong, Hong Ming, Lan Liu, En-Min Zhou, Yi-Rui Yin, Min Tseng, Yan-Yan Duan, Guo-Xing Nie, and Wen-Jun Li. Zhizhonghella caldifontis gen. nov., sp. nov., a novel member of the family Comamonadaceae. Antonie Van Leeuwenhoek Journal of Microbiology. 2014, 105(4):775-761. Hong Ming, Yi-Rui Yin, Shuai Li, Guo-Xing Nie*, Tian-Tian Yu, En-Min Zhou, Lan Liu, Lei Dong, Wen-Jun Li*.Thermus caliditerrae sp. nov., a novel thermophilic 1 species isolated from a geothermal area. International Journal of Systematic and Evolutionary Microbiology. (2014), 64:650-656. Tian-Tian, Yu En-Min, Zhou Yi-Rui Yin, Ji-Cheng Yao, Hong Ming, Lei Dong, Shuai Li, Guo-Xing Nie*, Wen-Jun Li*. Vulcaniibacterium tengchongense gen. nov., sp. nov. isolated from a geothermally heated soil sample, and reclassification of Lysobacter thermophilus Wei et al. 2012 as Vulcaniibacterium thermophilum comb. nov. Antonie Van Leeuwenhoek Journal of Microbiology. 2013,104:369-376. Kai Chen,Shu-Kun Tang, Guang-Li Wang, Guo-Xing Nie, Qin-Fen Li, Ji-Dong Zhang, Wen-jun Li*, Shun-Peng Li. Olivibacter jilunii sp. nov., isolated from a DDT-contaminated soil. International Journal of Systematic and Evolutionary Microbiology. 2013, 63:1083-1088. Guo-xing Nie¶*, Xiao Yan¶, Jun-li Wang, Hong Ming, Bei Wang, Jun-lin Zheng, Xue-jun Li, Xiang-hui Kong. Peptide Transporter PepT1 in Cyrinus Carpio’s Intestine: cDNA Cloning and Sequence Analysis. Turkish Journal of Biochemistry . 2012, 37(2):204-211. Guo-xing Nie¶*, Bei Wang¶, Jun-li Wang, Hong Ming, Jun-lin Zheng, Xue-jun Li, Xiang-hui Kong. Molecular cloning, sequence analysis and structure prediction of rBAT in Cyprinus carpio L. African Journal of Biotechnology. 2012, 11(32):8060-8069. Guo-Xing Nie¶, Hong Ming¶, Shu-Kun Tang, Xia Tang, Juan Cheng, Wen-Jun Li. Pseudonocardia yuanmoensis sp.nov., a novel actinobacterium isolated from soil in Yunnan, south-west China. Antonie Van Leeuwenhoek Journal of Microbiology. 2012, 101(4):753-760. Guo-Xing Nie¶, Hong Ming¶, Shuai-Li, En-Min Zhou, Juan Cheng, Xia Tang, Hui-Gen Feng, Shu-Kun Tang & Wen-Jun Li. Amycolatopsis dongchuanensis sp. nov., an actinobacterium isolated from soil. International Journal of Systematic and Evolutionary Microbiology. 2012, 62(11):2650-2656. Guo-Xing Nie¶, Hong Ming¶, Shuai Li, En-Min Zhou, Juan Cheng, Tian-Tian Yu, Jing Zhang, Hui-Gen Feng, Shu-Kun Tang & Wen-Jun Li.Geodermatophilus nigrescens sp. nov., isolated from a dry-hot valley.Antonie Van Leeuwenhoek Journal of Microbiology. 2012, 101(4):811-817. Guo-Xing Nie¶, Hong Ming¶, Jing Zhang, Hui-Gen Feng, Shuai Li, Tian-Tian Yu, En-Min Zhou, Wen-Jun Li. Kineococcus glutineturens sp. nov., isolated from soil in Yunnan, south-west China. Antonie Van Leeuwenhoek Journal of Microbiology. 2012,102(2):239-246. Guo-xing Nie¶*, Cai-xia Hou¶, Jun-li Wang, Jian-xin Zhang, Dong-ying Song, Bei Wang, Xue-jun Li, Xiang-hui Kong. Molecular cloning and sequence analysis of sglt1 and tertiary structure prediction of deduced protein in Cyprinus carpio L. Life Science Journal. 2011,8(2):204-212. Hong Ming¶, Guo-Xing Nie¶, Hong-Chen Jiang, Tian-Tian Yu, En-Min Zhou, Hui-Gen Feng, Shu-Kun Tang, Wen-Jun Li. Paenibacillus frigoriresistens sp. nov., a novel psychrotroph isolated from a peat bog in Heilongjiang, Northern China. Antonie Van Leeuwenhoek Journal of Microbiology. 2012, 102(2):297-305. En-Min Zhou, Shu-Kun Tang, Carsten Sjøholm, Zhao-Qi Song, Tian-Tian Yu, Ling-Ling Yang, Hong Ming, Guo-Xing Nie, Wen-Jun Li*. Thermoactinospora rubra gen. nov., sp. nov., a thermophilic actinomycete isolated from Tengchong, Yunnan province, south–west China. Antonie Van Leeuwenhoek Journal of Microbiology. 2012, 102(1):177-185. Xianglin Cao, Jianjun Chen, Junli Wang, Guoxing Nie*. Study of Enzymolysis Kinetics with Four Kinds of Protein Feeds in Megalobrama amblycephala in Vitro. Journal of Animal and Veterinary Advances. 2012, 11(9):1378-1384. Xianhui Kong, Shuping Wang, Hongxia Jiang, Guoxing Nie, Xuejun Li. Responses of acid/alkaline phosphatase, lysozyme, and catalase activities and lipid peroxidation to mercury exposure during the embryonic development of goldfish Carassius auratus. Aquatic Toxicology. 2012,120-121:119-125. Jie He, Ying Xu, Maloy Kumar Sahu, Xin-Peng Tian, Guo-Xing Nie, Qiong Xie, Si Zhang, Kannan Sivakumar*,Wen-Jun Li*. Actinomadura sediminis sp. nov., a marine actinomycete isolated from mangrove sediment. International Journal of Systematic and Evolutionary Microbiology. 2012, 62:1110-1116. Xia Tang, Yu Zhou, Jin Zhang, Hong Ming, Guo-xing Nie, Ling-ling Yang, Shu-kun Tang*, Wen-jun Li*. Actinokineospora soli sp. nov., a thermotolerant actinomycete isolated from soil, and emended description of the genus Actinokineospora. International Journal of Systematic and Evolutionary Microbiology. 2012, 62(8):1845-1849. En-min Zhou, Ling-ling Yang, Zhao-qi Song, Tian-tian Yu, Guo-xing Nie, Hong Ming, Yu Zhou, Shu-kun Tang, Wen-jun Li*. Thermocatellispora tengchongensis gen. nov., sp. nov., a new member of the family Streptosporangiaceae. International Journal of Systematic and Evolutionary Microbiology. 2012, 62(10):2417-2423 Salam Nimaichand, Wen-Yong Zhu, Ling-Ling Yang, Hong Ming, Guo-Xing Nie, Shu-Kun Tang, Debananda S. Ningthoujam, Wen-Jun Li*. Streptomyces manipurensis sp. nov., a novel actinomycete isolated from a limestone deposit site in Manipur, India. Antonie Van Leeuwenhoek Journal of Microbiology. 2012, 102(1):133-139. 2,、中文期刊論文(2012-2014) 孫君君,盧榮華,楊峰,秦超彬,孔祥會(huì),李學(xué)軍,聶國興. 草魚SREBP-1基因的克隆及糖對(duì)其在肝臟中表達(dá)的影響. 水產(chǎn)學(xué)報(bào),2014（審稿中）. 王俊麗,雒燕婷,郝光,閆瀟,吳春,聶國興*. 地黃和小肽對(duì)鯉魚生長性能及IL-8表達(dá)的調(diào)節(jié). 水產(chǎn)科學(xué), 2014（審稿中）. 單金峰,王俊麗,朱浩擁,吳春,聶國興*. 飼料中添加低聚木糖調(diào)控鯉魚免疫力和生長性能的研究. 水產(chǎn)科學(xué), 2014（審稿中）. 梁俊平,馬洪瑞,李健*,聶國興. 二氟沙星在大菱鲆體內(nèi)的藥代動(dòng)力學(xué)研究. 水產(chǎn)科學(xué), 2014（審稿中）. 梁俊平,李健*,李吉濤,劉萍,趙法箴,聶國興,李學(xué)軍,孔祥會(huì). 鹽度對(duì)脊尾白蝦親蝦抱卵及其子代生長發(fā)育的影響. 應(yīng)用生態(tài)學(xué)報(bào), 2014（待發(fā)表）. 王俊麗,郝光,雒燕婷,劉臻,孔祥會(huì),李學(xué)軍,聶國興*. 鯽魚TLR9基因克隆及其表達(dá)的生殖調(diào)控. 中國水產(chǎn)科學(xué),2014（待發(fā)表）. 馮軍廠,劉臻,魯雙慶,聶國興,周玲,孫浪. 草魚小肽轉(zhuǎn)運(yùn)載體PepT1基因的克隆與表達(dá)特征. 中國水產(chǎn)科學(xué),2013,20(2):276-285. 王俊麗,雒燕婷,郝光,孫君君,段艷艷,盧榮華,李學(xué)軍,孔祥會(huì),聶國興*. 淇河鯽IL-8 cDNA克隆及組織表達(dá)分析. 水產(chǎn)學(xué)報(bào),2013,37(9):1281-1289. 李學(xué)軍,郭瑄,聶國興,孔祥會(huì),喬志剛. 慢性鹽度脅迫對(duì)吉麗羅非魚（尼羅羅非魚♀×薩羅羅非魚♂）及其兩親本耐鹽性的影響. 水產(chǎn)學(xué)報(bào),2013,37(2):256-262. 郭瑄,李學(xué)軍,聶國興,孔祥會(huì). 吉麗羅非魚（尼羅羅非魚♀×薩羅羅非魚♂）及其兩親本遺傳變異的微衛(wèi)星分析.四川動(dòng)物,2013,32(3):321-324. 張敬,何偉宏,唐蜀昆,周恩民,明紅,李帥,聶國興,李文均. 云南干熱環(huán)境可培養(yǎng)高溫放線菌多樣性及產(chǎn)纖維素酶活性評(píng)價(jià).微生物學(xué)通報(bào),2013,40(6):1109-1120. 張建新,劉起麗,胡文波,聶國興*,韓科芳,趙 杰. 內(nèi)生枯草芽孢桿菌HD-1β-甘露聚糖酶基因的克隆及結(jié)構(gòu)生物學(xué)分析.河南師范大學(xué)學(xué)報(bào)(自然科學(xué)版), 2013,41(1):126-129. 馮軍廠,聶國興*,劉臻,張建社,王賞初,魯雙慶. 草魚Aminopeptidase N基因的克隆及表達(dá)特征分析. 水產(chǎn)學(xué)報(bào),2012,36(6):859-867. 聶國興*,王貝,閆瀟,侯彩霞,張建新,張新勝,鄭俊林,王俊麗.鯉魚腸道 sglt1的表達(dá)與抗體制備. 水產(chǎn)學(xué)報(bào),2012,36(3):329-335. 張建新,張噸,王海磊,韓科芳,趙 杰,聶國興*. 內(nèi)生菌產(chǎn)β-mannanase條件優(yōu)化及底物特異性研究. 食品研究與開發(fā), 2013,34(16):100-104. 楊心意,張峰,任萬增,聶國興,李帥,明紅,唐蜀昆,張利莉,李文均.響應(yīng)面法優(yōu)化Anoxybacillus sp.YIM 342 產(chǎn)耐高溫α-淀粉酶發(fā)酵條件.云南大學(xué)學(xué)報(bào)(自然科學(xué)版),2012,34(4):490-496. 王貝,王俊麗,閆瀟,張建新,侯彩霞,聶國興*.3種菌種產(chǎn)木聚糖酶同工酶及其酶解產(chǎn)物的比較.西北農(nóng)業(yè)學(xué)報(bào),2012,21(4):159-163. 3、出版著作 聶國興（主編）.《生物制品學(xué)》, 科學(xué)出版社, 2008年8月第一版（ISBN 978-7-03-022575-7）,，2012年5月第二版（ISBN 978-7-03-034097-9）. 2013年被遴選為第一批河南省“十二五”普通高等教育規(guī)劃教材,； 聶國興（主編）.《酶工程》, 科學(xué)出版社, 2013年6月第一版（ISBN 978-7-03-037503-2）； 聶國興（副主編）.《水產(chǎn)動(dòng)物營養(yǎng)與飼料學(xué)實(shí)驗(yàn)教程》, 中國農(nóng)業(yè)出版社, 2011年1月第一版（ISBN 978-7-109-15345-5）,。
五,、培養(yǎng)理念 1、善于交流,、敢于質(zhì)疑,，能從感性認(rèn)知中獲取理性精華； 2,、愉快學(xué)習(xí),、快樂生活，用陽光般的心態(tài)打造陽光未來,。 六,、招生意向 招生專業(yè)：水產(chǎn)養(yǎng)殖學(xué)（090801） 漁業(yè)（095108） 水產(chǎn)飼料工程（04） 招生人數(shù)：2-3人/年 通訊地址：河南師范大學(xué)水產(chǎn)學(xué)院 E-mail：[email protected] [email protected] 郵政編碼：453007
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